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recombinant human adamts5 protein  (R&D Systems)


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    Structured Review

    R&D Systems recombinant human adamts5 protein
    Recombinant Human Adamts5 Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 25 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+adamts5+protein/Recombinant+Human+ADAMTS5+Protein%2C+CF/pm41891882-80-12-16
    Average 94 stars, based on 25 article reviews
    recombinant human adamts5 protein - by Bioz Stars, 2026-11
    94/100 stars

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    Related Articles

    Recombinant:

    Article Title: Structure and interactions of hyaluronic acid, a model polyelectrolyte
    Article Snippet: .. Recombinant human ADAMTS5 protein from R&D systems, 20 μg, was purchased as a lyophilized powder and reconstituted in 100 μL ultrapure water, giving a protein concentration of 200 μg/mL in 740 mM NaCl, 18.5 mM sodium acetate, and 7.4 mM CaCl2. ..

    Article Title: Establishment of an Ex Vivo Cartilage Degeneration Model by Combined Collagenase and Aggrecanase Treatment and Mechanical Loading
    Article Snippet: Collagenase II, HBSS, and SuperScript Vilo RT Kit were supplied by ThermoFisher. .. Recombinant human ADAMTS4 protein (aggrecanase 1) and recombinant human ADAMTS5 protein (aggrecanase 2) were purchased from R&D Systems. ..

    Article Title: Establishment of an ex vivo cartilage damage model by combined collagenase treatment and mechanical loading.
    Article Snippet: Collagenase II, HBSS, and SuperScript Vilo RT Kit were supplied by ThermoFisher. .. Recombinant human ADAMTS4 protein (aggrecanase 1) and recombinant human ADAMTS5 protein (aggrecanase 2) were purchased from R&D Systems. ..

    Article Title: Identification of ADAMTS5 as APP-Cleaving Enzyme at the APP669 Site.
    Article Snippet: Cerebral amyloidβ (Aβ) deposition is a pathological hallmark of the earliest phases of Alzheimer disease (AD).. We previously reported APP669711 as a novel Aβrelated peptide detectable in human plasma and developed a composite biomarker that combines APP669711/Aβ142 and Aβ140/Aβ142 ratios to serve as a plasma surrogate of cerebral Aβ burden.. We also identified ADAMTS4 (a disintegrin and metalloproteinase with thrombospondin type 1 motif 4) as an APP669cleaving enzyme that catalyzes the ratelimiting step of APP669711 production.

    Article Title: Establishment of an ex vivo cartilage damage model by combined collagenase treatment and mechanical loading
    Article Snippet: Collagenase II, HBSS, and SuperScript Vilo RT Kit were supplied by ThermoFisher. .. Recombinant human ADAMTS4 protein (aggrecanase 1) and recombinant human ADAMTS5 protein (aggrecanase 2) were purchased from R&D Systems. ..

    Protein Concentration:

    Article Title: Structure and interactions of hyaluronic acid, a model polyelectrolyte
    Article Snippet: .. Recombinant human ADAMTS5 protein from R&D systems, 20 μg, was purchased as a lyophilized powder and reconstituted in 100 μL ultrapure water, giving a protein concentration of 200 μg/mL in 740 mM NaCl, 18.5 mM sodium acetate, and 7.4 mM CaCl2. ..

    Incubation:

    Article Title: Identification of ADAMTS5 as APP-Cleaving Enzyme at the APP669 Site.
    Article Snippet: Cerebral amyloidβ (Aβ) deposition is a pathological hallmark of the earliest phases of Alzheimer disease (AD).. We previously reported APP669711 as a novel Aβrelated peptide detectable in human plasma and developed a composite biomarker that combines APP669711/Aβ142 and Aβ140/Aβ142 ratios to serve as a plasma surrogate of cerebral Aβ burden.. We also identified ADAMTS4 (a disintegrin and metalloproteinase with thrombospondin type 1 motif 4) as an APP669cleaving enzyme that catalyzes the ratelimiting step of APP669711 production.

    other:

    Article Title: ADAMTS binding immunoglobulins
    Article Snippet: Subsequently, phages were prepared according to standard protocols (see for example the prior art and applications filed by Ablynx N.V. cited herein.) and stored after filter sterilization at 4° C. for further use.



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